Anti-MRSA agent 2

Names

[ CAS No. ]:
2597082-01-2

[ Name ]:
Anti-MRSA agent 2

Biological Activity

[Description]:

Anti-MRSA agent 2 (compound 14) has highly inhibitory activity against Methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.098 μg/ml, and relatively low cytotoxicity in normal cells. Anti-MRSA agent 2 has strong ability to destroy bacterial membrane and bind to genomic DNA[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[Target]

MIC: 0.098 μg/ml (MRSA)[1]


[References]

[1]. Wang X, et al. Fascaplysin derivatives binding to DNA via unique cationic five-ring coplanar backbone showed potent antimicrobial/antibiofilm activity against MRSA in vitro and in vivo. Eur J Med Chem. 2022;230:114099.

Chemical & Physical Properties

[ Molecular Formula ]:
C18H10Br2N2O

[ Molecular Weight ]:
430.09

Related Compounds