(2R,3S)-Brassinazole

Names

[ Name ]:
(2R,3S)-Brassinazole

Biological Activity

[Description]:

Brassinazole (0.5, 1, 5 μM) causes markedly deformed seedlings, whose morphology is similar to that of BR-deficient mutants. Brassinazole causes cress dwarfism, altering leaf morphology such as the typical downward curl and dark green appearance of Arabidopsis BR-deficient mutants. However, administration of 10 nM BR reversed dwarfism[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[Target]

Brassinosteroid (BR) biosynthesis[1]

[In Vitro]

Brassinazole (0.5, 1, 5 μM) 显着导致幼苗畸形，其形态与 BR 缺陷突变体相似。Brassinazole 会导致水芹侏儒症，改变叶片形态，例如拟南芥 BR 缺陷突变体会有的典型的向下卷曲和深绿色外观。然而，施用 10 nM BR可逆转侏儒症[1]。

[References]

[1]. Yoshida Shigeo, et al. Preparation of (1,2,4-triazolyl)alkanols as specific inhibitors of brassinosteroid biosynthesis: Japan, JP2000053657. 2000-02-22.

[2]. Asami T, et al. Mode of action of brassinazole: a specific inhibitor of brassinosteroid biosynthesis[M]. 2000.

[3]. T Asami, et al. Characterization of Brassinazole, a Triazole-Type Brassinosteroid Biosynthesis Inhibitor. Plant Physiol. 2000 May;123(1):93-100.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₁₈ClN₃O

[ Molecular Weight ]:
327.81

Related Compounds

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