DL-Selenomethionine
Names
[ CAS No. ]:
2578-28-1
[ Name ]:
DL-Selenomethionine
[Synonym ]:
MFCD00063089
DL-SELENOMETHIONINE-13C1 (METHYL-13C) 99
(+-)-butanoicaci
DL-Selenomethionine
seleno-D,L-methionine
EINECS 215-977-0
2-AMINO-4-(METHYLSELENO)BUTYRIC ACID
D,L-2-AMINO-4-(METHYLSELENO)BUTANOIC ACID
2-amino-4-methylselenobutanoic acid
2-Amino-4-(methylselanyl)butanoic acid
D L-SELENOMETHIONINE
AURORA KA-6143
DL-SELENOMETHIOININE
rac-(2R*)-2-[2-(Methylseleno)ethyl]glycine
selenium methionine
Chemical & Physical Properties
[ Boiling Point ]:
320.8ºC at 760 mmHg
[ Melting Point ]:
267-269 °C
[ Molecular Formula ]:
C5H10NO2SSe
[ Molecular Weight ]:
227.16300
[ Flash Point ]:
147.8ºC
[ Exact Mass ]:
227.96000
[ PSA ]:
74.96000
[ LogP ]:
0.65730
[ Storage condition ]:
−20°C
[ Water Solubility ]:
0.5 M HCl: 50 mg/mL, clear, colorless
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- ES7110000
- CHEMICAL NAME :
- Butyric acid, 2-amino-4-(methylselenyl)-, DL-
- CAS REGISTRY NUMBER :
- 2578-28-1
- BEILSTEIN REFERENCE NO. :
- 1758204
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 29
- MOLECULAR FORMULA :
- C5-H11-N-O2-Se
- MOLECULAR WEIGHT :
- 196.13
- WISWESSER LINE NOTATION :
- QVYZ2-SE-1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10680 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 19600 ug/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - pig
- DOSE/DURATION :
- 77035 ug/kg/31D-C
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Blood - other changes Skin and Appendages - dermatitis, other (after systemic exposure)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - duck
- DOSE/DURATION :
- 84 mg/kg/6W-C
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases Biochemical - Metabolism (Intermediary) - other proteins
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - duck
- DOSE/DURATION :
- 314 mg/kg/14W-C
- TOXIC EFFECTS :
- Liver - changes in liver weight Blood - pigmented or nucleated red blood cells Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases
MUTATION DATA
- TYPE OF TEST :
- Unscheduled DNA synthesis
- TEST SYSTEM :
- Rodent - rat Liver
- DOSE/DURATION :
- 100 umol/L
- REFERENCE :
- CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 10,75,1980 *** REVIEWS *** ACGIH TLV-TWA 0.2 mg(Se)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 0.2 mg(Se)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,224,1971 OSHA PEL (Gen Indu):8H TWA 0.2 mg(Se)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.2 mg(Se)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 0.2 mg(Se)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.2 mg(Se)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-ARAB Republic of Egypt:TWA 0.2 mg(Se)/m3 JAN 1993 OEL-AUSTRALIA:TWA 0.2 mg(Se)/m3 JAN 1993 OEL-BELGIUM:TWA 0.2 mg(Se)/m3 JAN 1993 OEL-DENMARK:TWA 0.1 mg(Se)/m3 JAN 1993 OEL-FINLAND:TWA 0.1 mg(Se)/m3;STEL 0.3 mg(Se)/m3 JAN 1993 OEL-GERMANY:TWA 0.1 mg(Se)/m3 JAN 1993 OEL-HUNGARY:STEL 0.1 mg(Se)/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 0.2 mg(Se)/m3 JAN 1993 OEL-THE PHILIPPINES:TWA 0.2 mg(Se)/m3 JAN 1993 OEL-POLAND:TWA 0.1 mg(Se)/m3 JAN 1993 OEL-SWEDEN:TWA 0.1 mg(Se)/m3 JAN 1993 OEL-SWITZERLAND:TWA 0.1 mg(Se)/m3 JAN 1993 OEL-TURKEY:TWA 0.2 mg(Se)/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 0.1 mg(Se)/m3 JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV
Safety Information
[ Hazard Codes ]:
T,N
[ Risk Phrases ]:
23/25-33-50/53
[ Safety Phrases ]:
S20/21-S28-S45-S60-S61
[ RIDADR ]:
UN 3283 6.1/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
ES7110000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1(a)
[ HS Code ]:
2922499990
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922499990
[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%