NRP1 antagonist 1

Names

[ CAS No. ]:
2569598-01-0

[ Name ]:
NRP1 antagonist 1

Biological Activity

[Description]:

NRP1 antagonist 1 (compound 12a) is a potent NRP1 antagonist with an IC50 of 19.1 μM. NRP1 antagonist 1 has the potential for cancer research[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Immunology/Inflammation >> Complement System

[References]

[1]. Kewen Peng, et al. Discovery of novel nonpeptide small-molecule NRP1 antagonists: Virtual screening, molecular simulation and structural modification. Bioorg Med Chem. 2020 Jan 1;28(1):115183.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H22N6OS2

[ Molecular Weight ]:
450.58

Related Compounds