Flonoltinib maleate

Names

[ Name ]:
Flonoltinib maleate

Biological Activity

[Description]:

Flonoltinib maleate is a potent, highly selective, dual JAK2/FLT3 inhibitor with IC50 of 0.8, 1.4, and 15 nM for JAK2, JAK2V617F, and FLT3, respectively.

[References]

1. Hu M, et al. Blood Cancer J. 2022 Mar 7;12(3):37. 2. Zhu J, et al. Biomed Pharmacother. 2021 May;137:111373.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₉H₃₈FN₇O₅

[ Molecular Weight ]:
583.665

Related Compounds

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