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METHOXYPROMAZINE MALEATE

Names

[ CAS No. ]:
3403-42-7

[ Name ]:
METHOXYPROMAZINE MALEATE

[Synonym ]:
Methopromazinhydrogenmaleat
2-Methoxypromazine maleate
Mopazine maleate
Methopromazine maleate
2-Methoxypromazin-maleat
Mopazine
EINECS 222-277-9
Methoxypromazine maleate
Tentone maleate
Metopromazine maleate

Chemical & Physical Properties

[ Boiling Point ]:
461.8ºC at 760mmHg

[ Molecular Formula ]:
C22H26N2O5S

[ Molecular Weight ]:
430.51700

[ Flash Point ]:
233.1ºC

[ Exact Mass ]:
430.15600

[ PSA ]:
115.61000

[ LogP ]:
4.02640

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SO7700000
CAS REGISTRY NUMBER :
3403-42-7
LAST UPDATED :
199712
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C18-H22-N2-O-S.C4-H4-O4
MOLECULAR WEIGHT :
430.56
WISWESSER LINE NOTATION :
T C666 BN ISJ B3N1&1 EO1 &OV1U1VO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
730 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,32,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
130 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 125,101,1960
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
420 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,32,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
120 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,32,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,32,1972

Safety Information

[ HS Code ]:
2934300000

Customs

[ HS Code ]: 2934300000

[ Summary ]:
2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds

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