FR221647

Names

[ CAS No. ]:
256461-28-6

[ Name ]:
FR221647

[Synonym ]:
1H-Imidazole-4-carboxamide,1-[1-(hydroxymethyl)-3-phenylpropyl]

Biological Activity

[Description]:

FR221647 is an orally active non-nucleoside inhibitor of adenosine deaminase. FR221647 is not cytotoxic at a concentration of 100 μM[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Metabolic Enzyme/Protease >> Adenosine Deaminase

[References]

[1]. Terasaka T, et al. Structure-based de novo design of non-nucleoside adenosine deaminase inhibitors. Bioorg Med Chem Lett. 2003 Mar 24;13(6):1115-8.  

Chemical & Physical Properties

[ Molecular Formula ]:
C14H17N3O2

[ Molecular Weight ]:
259.30

[ Exact Mass ]:
259.13200

[ PSA ]:
82.13000

[ LogP ]:
2.03240

Related Compounds

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