RIPK1-IN-16

Names

[ Name ]:
RIPK1-IN-16

Biological Activity

[Description]:

RIPK1-IN-16 is an orally active and potent inhibitor of RIPK1. RIPK1-IN-16 inhibits excessive inflammation by blocking RIPK1-mediated necroptosis in vivo. RIPK1-IN-16 protects mouse from TNF-induced systemic inflammatory response syndrome and sepsis[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> RIP kinase

Research Areas >> Inflammation/Immunology

[References]

[1]. Ling ZY, et al. Protective Effect of a Novel RIPK1 Inhibitor, Compound 4-155, in Systemic Inflammatory Response Syndrome and Sepsis. Inflammation. 2023 Oct;46(5):1796-1809.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₁₉N₅O₂S

[ Molecular Weight ]:
393.46

Related Compounds

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