2561431-77-2

2561431-77-2 structure

Name: RIPK1-IN-16
Chemical Name: RIPK1-IN-16
CAS Number: 2561431-77-2
Molecular Formula: C₂₀H₁₉N₅O₂S
Molecular Weight: 393.46
Catalog: Signaling Pathways Apoptosis RIP kinase
Create Date: 2023-12-26 17:58:00
Modify Date: 2024-01-11 10:23:56
RIPK1-IN-16 is an orally active and potent inhibitor of RIPK1. RIPK1-IN-16 inhibits excessive inflammation by blocking RIPK1-mediated necroptosis in vivo. RIPK1-IN-16 protects mouse from TNF-induced systemic inflammatory response syndrome and sepsis[1].

Name	RIPK1-IN-16

Description	RIPK1-IN-16 is an orally active and potent inhibitor of RIPK1. RIPK1-IN-16 inhibits excessive inflammation by blocking RIPK1-mediated necroptosis in vivo. RIPK1-IN-16 protects mouse from TNF-induced systemic inflammatory response syndrome and sepsis[1].
Related Catalog	Signaling Pathways >> Apoptosis >> RIP kinase Research Areas >> Inflammation/Immunology
References	[1]. Ling ZY, et al. Protective Effect of a Novel RIPK1 Inhibitor, Compound 4-155, in Systemic Inflammatory Response Syndrome and Sepsis. Inflammation. 2023 Oct;46(5):1796-1809.

Molecular Formula	C₂₀H₁₉N₅O₂S
Molecular Weight	393.46