Pachybasin

Names

[ Name ]:
Pachybasin

[Synonym ]:
3-methyl-1-hydroxyanthraquinone
1-hydroxy-3-methyl-5,10-anthraquinone
1-Hydroxy-3-methyl-2-chinoxalin-4-oxyd
1-hydroxy-3-methylanthraquinone
1-hydroxy-3-methyl-1H-quinoxalin-2-one
1-hydroxy-3-methylanthracene-9,10-dione
1-HYDROXY-3-METHYLQUINOXALIN-2(1H)-ONE

Biological Activity

[Description]:

Pachybasin is a major metabolite from culture broth of endophytic coelomyceteous AFKR-18 fungus. Pachybasin showes antimicrobial activities against E. coli, B. subtilis, M. luteus, S. cerevisiae, C. albicans, A. niger, and A. flavus, with MIC values of 64.0 μg/mL, and against S. aureus and F. oxysporum with MIC values of 32.0 and 16.0 μg/mL respectively[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. DEWIWULANSARI, et al. Pachybasin, a Major Metabolite from Culture Broth of Endophytic Coelomyceteous AFKR-18 Fungus isolated from a Yellow Moonsheed Plant, Arcangelisia flava (L.) Merr.

Chemical & Physical Properties

[ Density]:
1.371g/cm3

[ Boiling Point ]:
453.1ºC at 760 mmHg

[ Molecular Formula ]:
C₁₅H₁₀O₃

[ Molecular Weight ]:
238.23800

[ Flash Point ]:
241.9ºC

[ Exact Mass ]:
238.06300

[ PSA ]:
54.37000

[ LogP ]:
2.47600

[ Vapour Pressure ]:
7.94E-09mmHg at 25°C

[ Index of Refraction ]:
1.676

Safety Information

[ HS Code ]:
2914690090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914690090

[ Summary ]:
2914690090 other quinones。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%