(2E,4E)-Deca-2,4-dienal

Names

[ Name ]:
(2E,4E)-Deca-2,4-dienal

[Synonym ]:
DDA
FEMA 3135
DECADIENEALDEHYDE
(2E,4E)-2,4-Decadienal
2,4-Decadienal, (2E,4E)-
2E,4E-DECADIENAL
2,4-Decadienal
(2E,4E)-Deca-2,4-dienal
trans,trans-2,4-Decadienal
2,4-DECADIEN-1-AL
trans-2,4-Decadienal
trans,trans-deca-2,4-dienal
2-trans,4-trans-n-decadienal
Decadienal
2,4-trans,trans-decadienal
2-trans,4-trans decadienal
EINECS 246-668-9
T2 T4 DECADIENAL
2.4-Decadienal
MFCD00007007

Biological Activity

[Description]:

trans,trans-2,4-Decadienal is a lipid peroxidation product of linolieic acid[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Two metabolic pathways for the biotransformation of trans,trans-2,4-Decadienal (tt-DDE) in vivo are proposed: (i) the oxidation of tt-DDE to the corresponding carboxylic acid, 2,4-decadienoic acid, in liver cells and (ii) glutathione (GHS) conjugation, GSH breakdown, and aldehyde reduction, which generate cysteine-conjugated 2,4-decadien-1-ol in both liver and lung cells.

[References]

[1]. Kao-Lu Pan, et al. Identification of trans,trans-2,4-decadienal metabolites in mouse and human cells using liquid chromatography-mass spectrometry. Chem Res Toxicol. 2014 Oct 20;27(10):1707-19.

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
244.6±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₀H₁₆O

[ Molecular Weight ]:
152.233

[ Flash Point ]:
102.3±11.0 °C

[ Exact Mass ]:
152.120117

[ PSA ]:
17.07000

[ LogP ]:
3.18

[ Vapour density ]:
>1 (vs air)

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.459

[ Storage condition ]:
Refrigerator (+4°C)

[ Water Solubility ]:
insoluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HD3000000

CHEMICAL NAME :: 2,4-Decadienal, (E,E)-

CAS REGISTRY NUMBER :: 25152-84-5

BEILSTEIN REFERENCE NO. :: 1704897

LAST UPDATED :: 199712

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C10-H16-O

MOLECULAR WEIGHT :: 152.26

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
HD3000000

[ Packaging Group ]:
III

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Olfactometry Profiles and Quantitation of Volatile Sulfur Compounds of Swiss Tilsit Cheeses.

J. Agric. Food Chem. 63 , 7511-21, (2015)

To establish the odor profiles of three differently fabricated commercial Swiss Tilsit cheeses, analyses were conducted using headspace solid-phase microextraction gas chromatography-mass spectrometry...

Characterization of Volatile Flavor Compounds in Chinese Rice Wine Fermented from Enzymatic Extruded Rice.

J. Food Sci. 80 , C1476-89, (2015)

Enzymatic extrusion, instead of traditional steam cooking, to treat rice is an efficient and alternative pretreatment for Chinese rice wine fermentation. In order to determine the formation of volatil...

trans,trans-2,4-decadienal induces mitochondrial dysfunction and oxidative stress.

J. Bioenerg. Biomembr. 40(2) , 103-9, (2008)

Lipid peroxidation produces a large number of reactive aldehydes as secondary products. We have previously shown that the reaction of cytochrome c with trans,trans-2,4-decadienal (DDE), an aldehyde ge...

Related Compounds

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