N-acetyldopamine

Names

[ Name ]:
N-acetyldopamine

[Synonym ]:
N-(3,4-dihydroxy-phenethyl)-acetamide
Acetamide,N-(2-(3,4-dihydroxyphenyl)ethyl)
N-Acetyldopamine monohydrate
N-[2-(3,4-dihydroxybenzene)ethyl]acetamide
N-[2-(3,4-Dihydroxyphenyl)ethyl]acetamid
N-acetyl dopamine
Acetamide,N-(3,4-dihydroxyphenethyl)-(7CI,8CI)
Acetamide,N-(3,4-dihydroxyphenethyl)

Biological Activity

[Description]:

N-acetyldopamine (NADA) is a catecholamine that is used by insects as sclerotizing precursors to harden their cuticle[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Hanine Barek, et al. Unraveling Complex Molecular Transformations of N-β-alanyldopamine That Account for Brown Coloration of Insect Cuticle. Rapid Commun Mass Spectrom. 2017 Aug 30;31(16):1363-1373.

Chemical & Physical Properties

[ Density]:
1.235g/cm3

[ Boiling Point ]:
486.7ºC at 760mmHg

[ Molecular Formula ]:
C₁₀H₁₃NO₃

[ Molecular Weight ]:
195.21500

[ Flash Point ]:
248.1ºC

[ Exact Mass ]:
195.09000

[ PSA ]:
69.56000

[ LogP ]:
1.16730

[ Vapour Pressure ]:
4.27E-10mmHg at 25°C

[ Index of Refraction ]:
1.578

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AB7651000

CHEMICAL NAME :: Acetamide, N-(2-(3,4-dihydroxyphenyl)ethyl)-

CAS REGISTRY NUMBER :: 2494-12-4

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C10-H13-N-O3

MOLECULAR WEIGHT :: 195.24

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CTRRDO Cancer Treatment Reports. (Washington, DC) V.60-71, 1976-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 63,991,1979

Safety Information

[ Hazard Codes ]:
Xi

[ RTECS ]:
AB7651000

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%