Amino methacrylate copolymer
Names
[ CAS No. ]:
24938-16-7
[ Name ]:
Amino methacrylate copolymer
[Synonym ]:
Basic butylated methacrylate copolyme
Chemical & Physical Properties
[ Boiling Point ]:
187ºC at 760mmHg
[ Molecular Formula ]:
C21H37NO6
[ Molecular Weight ]:
399.522
[ Flash Point ]:
>250℃
[ Exact Mass ]:
399.262085
[ PSA ]:
82.14000
[ LogP ]:
3.30860
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- OZ3688000
- CHEMICAL NAME :
- Methacrylic acid, butyl ester, polymer with 2-(dimethylamino)ethyl methacrylate and methyl methacrylate
- CAS REGISTRY NUMBER :
- 24938-16-7
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 800 mg/kg
- REFERENCE :
- APHGAO Acta Pharmaceutica Hungarica. (Kultura, POB 149, H-1389 Budapest, Hungary) 1953- Adopts V.24 in 1955. Volume(issue)/page/year: 56,97,1986
Safety Information
[ RIDADR ]:
NONH for all modes of transport
Articles
Chem. Pharm. Bull. 60(11) , 1468-73, (2012)
In this study, amorphous solid dispersions containing dutasteride and various excipients, manufactured by spray-drying processes, were characterized to determine the effects on their ability to form s...
Effect of aminoalkyl methacrylate copolymer E/HCl on in vivo absorption of poorly water-soluble drug.Drug Dev. Ind. Pharm. 39(11) , 1698-705, (2013)
This study aimed to investigate in vivo absorption of tacrolimus formulated as a solid dispersion using Eudragit E®/HCl (E-SD). E-SD is an aminoalkyl methacrylate copolymer that can be dissolved under...
Eudragit E as excipient for production of granules and tablets from Phyllanthus niruri L spray-dried extract.AAPS PharmSciTech 8(2) , Article 34, (2007)
The aim of this study was to investigate the feasibility of using Eudragit E as a granulating agent for a spray-dried extract from Phyllanthus niruri to obtain tablets containing a high dose of this p...