N-Formylglycine
Names
[ CAS No. ]:
2491-15-8
[ Name ]:
N-Formylglycine
[Synonym ]:
EINECS 219-649-8
N-For-Gly-OH
MFCD00037360
Glycine,N-formyl
N-ForMylglycine
For-Gly-OH
2-Formamidoacetic acid
Formylglycine
Formylglycin
formylaminoacetic acid
FGly
N-Hydroxymethyleneglycine
Chemical & Physical Properties
[ Density]:
1.307 g/cm3
[ Boiling Point ]:
450.2ºC at 760 mmHg
[ Melting Point ]:
149-151 °C
[ Molecular Formula ]:
C3H5NO3
[ Molecular Weight ]:
103.07700
[ Flash Point ]:
226.1ºC
[ Exact Mass ]:
103.02700
[ PSA ]:
66.40000
[ Vapour Pressure ]:
2.33E-09mmHg at 25°C
[ Index of Refraction ]:
1.452
[ Storage condition ]:
2-8°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MC0547000
- CHEMICAL NAME :
- Glycine, N-formyl-
- CAS REGISTRY NUMBER :
- 2491-15-8
- BEILSTEIN REFERENCE NO. :
- 1749108
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C3-H5-N-O3
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >3 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DZMKAS Deutsche Zahn-, Mund- und Kieferheilkunde. (Leipzig, Ger. Dem. Rep.) V.1-62, 1934-74. Volume(issue)/page/year: 62,32,1974
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi: Irritant;
[ Safety Phrases ]:
S22-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
MC0547000
[ HS Code ]:
2924199090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2924199090
[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
J. Am. Chem. Soc. 130(37) , 12240-1, (2008)
Formylglycine generating enzyme (FGE) performs a critical posttranslational modification of type I sulfatases, converting cysteine within the motif CxPxR to the aldehyde-bearing residue formylglycine ...
The ribosome as an entropy trap.Proc. Natl. Acad. Sci. U. S. A. 101(21) , 7897-901, (2004)
To determine the effectiveness of the ribosome as a catalyst, we compared the rate of uncatalyzed peptide bond formation, by the reaction of the ethylene glycol ester of N-formylglycine with Tris(hydr...
Function and structure of a prokaryotic formylglycine-generating enzyme.J. Biol. Chem. 283(29) , 20117-25, (2008)
Type I sulfatases require an unusual co- or post-translational modification for their activity in hydrolyzing sulfate esters. In eukaryotic sulfatases, an active site cysteine residue is oxidized to t...