Axl-IN-9

Names

[ Name ]:
Axl-IN-9

Biological Activity

[Description]:

Axl-IN-9 (Example 10) is a potent AXL inhibitor, with an IC50 of 26 nM. Axl-IN-9 has excellent transmembrane properties. Axl-IN-9 exhibits excellent pharmacokinetic properties in an animal body. Axl-IN-9 can be used for the research of proliferative diseases, autoimmune diseases, allergic diseases, inflammatory diseases, transplant rejection, cancer, or other diseases in mammals[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> TAM Receptor

Research Areas >> Inflammation/Immunology

[Target]

IC50: 26 nM (AXL)[1]

[References]

[1]. Xi Ning. Substituted heteroaryl compound, composition of same, and uses thereof. WO2020182188A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₂₃N₇O₂

[ Molecular Weight ]:
453.50

Related Compounds

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