Influenza A virus-IN-5

Names

[ CAS No. ]:
2464415-12-9

[ Name ]:
Influenza A virus-IN-5

Biological Activity

[Description]:

Influenza A virus-IN-5 (Compound 16e) is a potent, orally active anti-influenza A virus (IAV) agent with an IC50 of 1.29 μM. Influenza A virus-IN-5 inhibits the transcription and replication of viral RNA with acceptable cytotoxicity[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Influenza Virus
Research Areas >> Infection
Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis

[References]

[1]. Zhang G, et al. Design, synthesis and in vitro anti-influenza A virus evaluation of novel quinazoline derivatives containing S-acetamide and NH-acetamide moieties at C-4. Eur J Med Chem. 2020 Nov 15;206:112706.

Chemical & Physical Properties

[ Molecular Formula ]:
C24H23N5O

[ Molecular Weight ]:
397.47

Related Compounds