Pyropheophorbide-alpha

Names

[ Name ]:
Pyropheophorbide-alpha

[Synonym ]:
pyro-pheophorbide a acid
3-[(3S,4S)-14-Ethyl-4,8,13,18-tetramethyl-20-oxo-9-vinyl-24,25-dihydro-3-phorbinyl]propanoic acid
31,32-didehydrophytochlorin
pyropheophorbidea
pyrophaeophorbide a
Pyropheophorbide a
3-Phorbinepropanoic acid, 9-ethenyl-14-ethyl-24,25-dihydro-4,8,13,18-tetramethyl-20-oxo-, (3S,4S)-
PYROPHEOPHORBIDE
Pyropheophorbide-alpha
Magnesium pyrophyllate a

Biological Activity

[Description]:

Pyropheophorbide-a (Ppa) is a promising photosensitizer for tumor photodynamic therapy (PDT)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Li W, et al. cRGD Peptide-Conjugated Pyropheophorbide-a Photosensitizers for Tumor Targeting in Photodynamic Therapy. Mol Pharm. 2018 Apr 2;15(4):1505-1514.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
991.5±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₃H₃₄N₄O₃

[ Molecular Weight ]:
534.648

[ Flash Point ]:
553.5±34.3 °C

[ Exact Mass ]:
534.263062

[ PSA ]:
110.67000

[ LogP ]:
6.49

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.665

Safety Information

[ Hazard Codes ]:
Xn

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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