17-ALPHA-ETHYNYL-19-NORTESTOSTERONE ACETATE OXIME
Names
[ CAS No. ]:
20799-24-0
[ Name ]:
17-ALPHA-ETHYNYL-19-NORTESTOSTERONE ACETATE OXIME
[Synonym ]:
Norethisterone acetate oxime
Norethisterone-3-oxime acetate
ORF 5263
Norethisterone acetate-3-oxime
So-36
Norethisterone oxime acetate
17alpha-Ethynyl-17beta-acetoxy-19-norandrost-4-en-3-one oxime
Chemical & Physical Properties
[ Density]:
1.24g/cm3
[ Boiling Point ]:
486.1ºC at 760mmHg
[ Molecular Formula ]:
C22H29NO3
[ Molecular Weight ]:
355.47100
[ Flash Point ]:
247.8ºC
[ Exact Mass ]:
355.21500
[ PSA ]:
58.89000
[ LogP ]:
4.32440
[ Vapour Pressure ]:
0mmHg at 25°C
[ Index of Refraction ]:
1.618
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RC8965500
- CHEMICAL NAME :
- 19-Norpregn-4-en-20-yn-3-one, 17-(acetyloxy)-, 3-oxime, (17-alpha)-
- CAS REGISTRY NUMBER :
- 20799-24-0
- LAST UPDATED :
- 199506
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C22-H29-N-O3
- MOLECULAR WEIGHT :
- 355.52
- WISWESSER LINE NOTATION :
- L E5 B666 OY MUTJ E1 FOV1 F1UU1 OUNQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 5 mg/kg
- SEX/DURATION :
- female 1-5 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
- REFERENCE :
- SCYYDZ Shengzhi Yu Biyun. Reproduction and Contraception. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) 1980- Volume(issue)/page/year: 10(3),67,1990
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 4 mg/kg
- SEX/DURATION :
- female 6-9 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
- REFERENCE :
- SCYYDZ Shengzhi Yu Biyun. Reproduction and Contraception. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) 1980- Volume(issue)/page/year: 10(3),67,1990
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1500 ug/kg
- SEX/DURATION :
- female 2-4 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
- REFERENCE :
- YHTPAD Yaoxue Tongbao. Bulletin of Pharmacology. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.13-23, 1978-88. For publisher information, see ZYZAEU. Volume(issue)/page/year: 16(6),53,1981
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 5 mg/kg
- SEX/DURATION :
- female 2 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
- REFERENCE :
- YHTPAD Yaoxue Tongbao. Bulletin of Pharmacology. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.13-23, 1978-88. For publisher information, see ZYZAEU. Volume(issue)/page/year: 16(6),53,1981
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 6 mg/kg
- SEX/DURATION :
- female 2-4 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
- REFERENCE :
- YHTPAD Yaoxue Tongbao. Bulletin of Pharmacology. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.13-23, 1978-88. For publisher information, see ZYZAEU. Volume(issue)/page/year: 16(6),53,1981
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 6 mg/kg
- SEX/DURATION :
- female 2-4 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
- REFERENCE :
- YHTPAD Yaoxue Tongbao. Bulletin of Pharmacology. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.13-23, 1978-88. For publisher information, see ZYZAEU. Volume(issue)/page/year: 16(6),53,1981