FOXO1-IN-3

Names

[ Name ]:
FOXO1-IN-3

Biological Activity

[Description]:

FOXO1-IN-3 is a highly-selective and orally active FOXO1 inhibitor. FOXO1-IN-3 reduces hepatic glucose production in mice. FOXO1-IN-3 improves insulin sensitivity and glucose control in db/db mice without causing weight gain[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[Target]

FOXO1[1]

[References]

[1]. Lee YK, et al. FOXO1 inhibition synergizes with FGF21 to normalize glucose control in diabetic mice. Mol Metab. 2021 Jul;49:101187.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₃N₇O

[ Molecular Weight ]:
401.46

Related Compounds

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