2451093-95-9

2451093-95-9 structure

Name: FOXO1-IN-3
Chemical Name: FOXO1-IN-3
CAS Number: 2451093-95-9
Molecular Formula: C₂₂H₂₃N₇O
Molecular Weight: 401.46
Catalog: Research Areas Metabolic Disease
Create Date: 2023-09-30 20:54:52
Modify Date: 2025-09-20 21:16:34
FOXO1-IN-3 is a highly-selective and orally active FOXO1 inhibitor. FOXO1-IN-3 reduces hepatic glucose production in mice. FOXO1-IN-3 improves insulin sensitivity and glucose control in db/db mice without causing weight gain[1].

Name	FOXO1-IN-3

Description	FOXO1-IN-3 is a highly-selective and orally active FOXO1 inhibitor. FOXO1-IN-3 reduces hepatic glucose production in mice. FOXO1-IN-3 improves insulin sensitivity and glucose control in db/db mice without causing weight gain[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
Target	FOXO1[1]
References	[1]. Lee YK, et al. FOXO1 inhibition synergizes with FGF21 to normalize glucose control in diabetic mice. Mol Metab. 2021 Jul;49:101187.

Molecular Formula	C₂₂H₂₃N₇O
Molecular Weight	401.46