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RSV-IN-2

Names

[ CAS No. ]:
2448519-26-2

[ Name ]:
RSV-IN-2

Biological Activity

[Description]:

RSV-IN-2 is a potent dual inhibitor of wild-type and mutant respiratory syncytial virus fusion proteins (wild-type, EC50 = 0.27 nM; D486N-mutant, EC50 = 0.70 nM).

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> RSV

[References]

[1]. Yamaguchi-Sasaki T, et al. Discovery of a potent dual inhibitor of wild-type and mutant respiratory syncytial virus fusion proteins through the modulation of atropisomer interconversion properties. Bioorg Med Chem. 2020 Dec 15;28(24):115818.

Chemical & Physical Properties

[ Molecular Formula ]:
C27H31ClN6O4

[ Molecular Weight ]:
539.03

Related Compounds