Antibacterial agent 111

Names

[ CAS No. ]:
2448358-84-5

[ Name ]:
Antibacterial agent 111

Biological Activity

[Description]:

Antibacterial agent 111 (Compound 3) is an antibacterial agent with MIC values of 3.90 μg/mL and 0.49 μg/mL against B. cereus and K. pneumonia, respectively. Antibacterial agent 111 firmly binds with tyrosyl-tRNA synthetase residues[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Antibacterial agent 111 (Compound 3) inhibits fungal strains with MIC values of both 250 μg/mL against A. flavus and A. ochraceus[1].

[References]

[1]. Othman IMM, et al. Design, synthesis ADMET and molecular docking of new imidazo[4,5-b]pyridine-5-thione derivatives as potential tyrosyl-tRNA synthetase inhibitors. Bioorg Chem. 2020 Sep;102:104105.

Chemical & Physical Properties

[ Molecular Formula ]:
C18H12N6S

[ Molecular Weight ]:
344.39

Related Compounds