H-Cys-Thr-Thr-His-Trp-Gly-Phe-Thr-Leu-Cys-OH (Disulfide bond)

Names

[ CAS No. ]:
244082-19-7

[ Name ]:
H-Cys-Thr-Thr-His-Trp-Gly-Phe-Thr-Leu-Cys-OH (Disulfide bond)

[Synonym ]:
h-cys-thr-thr-his-trp-gly-phe-thr-leu-cys-oh

Biological Activity

[Description]:

CTTHWGFTLC, CYCLIC is a cyclic peptide inhibitor for matrix metalloproteinases MMP-2 and MMP-9[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Metabolic Enzyme/Protease >> MMP

[Target]

MMP-2

MMP-9

[References]

[1]. Medina OP, et al. Binding of novel peptide inhibitors of type IV collagenases to phospholipid membranes and use in liposome targeting to tumor cells in vitro. Cancer Res. 2001 May 15;61(10):3978-85.

Chemical & Physical Properties

[ Molecular Formula ]:
C₅₂H₇₁N₁₃O₁₄S₂

[ Molecular Weight ]:
1166.33

[ Exact Mass ]:
1165.47000

[ PSA ]:
480.98000

[ LogP ]:
0.56840

Related Compounds

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