D-Luciferin 6′-methyl ether

Names

[ Name ]:
D-Luciferin 6′-methyl ether

[Synonym ]:
LucME
D-methoxyluc
lucifern 6'-methyl ether

Biological Activity

[Description]:

D-Luciferin 6′-methyl ether (6′-Methoxyluciferin; compound 19a) is a potent luciferase from the North American firefly Photinus pyralis (PpyLuc) inhibitor with an IC50 of 0.1 µM. D-Luciferin 6′-methyl ether, a D-luciferin analog, shows non-specific interactions at ATP- and luciferin-binding sites of the PpyLuc active site[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Giuseppe Meroni, et al. D-Luciferin, derivatives and analogues: synthesis and in vitro/in vivo luciferase-catalyzed bioluminescent activity. Volume 2009, Issue 1, Reviews and Accounts, pp. 265-288

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂H₁₀N₂O₃S₂

[ Molecular Weight ]:
294.34900

[ Exact Mass ]:
294.01300

[ PSA ]:
125.32000

[ LogP ]:
1.68710

Related Compounds

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