3CPLro-IN-1

Names

[ Name ]:
3CPLro-IN-1

Biological Activity

[Description]:

3CPLro-IN-1 (compound A17) is a potent and orally active inhibitor of SARS-CoV-2 3CLpro with an IC50 of 5.65 μM. 3-Chymotrypsin-like cysteine protease (3CLpro) is an indispensable protein in viral replication and represents an attractive drug target for fighting COVID-19[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Others >> Others

[References]

[1]. Zhang JW, et al. Discovery of 9,10-dihydrophenanthrene derivatives as SARS-CoV-2 3CLpro inhibitors for treating COVID-19. Eur J Med Chem. 2022;228:114030.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₉H₂₅NO₃

[ Molecular Weight ]:
435.51

Related Compounds

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