Boc-Glu-OtBu

Names

[ Name ]:
Boc-Glu-OtBu

[Synonym ]:
Boc-L-glutamicacid1-tert-butylester
Boc-L-glutamic acid 1-tert-butyl ester
MFCD00038273
N-(tert-Butoxycarbonyl)-L-glutamic Acid 1-tert-Butyl Ester
N-Boc-Glu-OtBu
N-(t-butoxycarbonyl)-L-glutamic acid t-butyl ester
Boc-Glu-Otbu
N-Boc-L-glutamic acid 1-tert-butyl ester
1-tert-Butyl N-(tert-Butoxycarbonyl)-L-glutamate
(S)-5-tert-butoxy-4-tert-butoxycarbonylamino-5-oxo-pentanoic acid
(4S)-5-[(2-Methyl-2-propanyl)oxy]-4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-5-oxopentanoic acid
5-[(2-Methyl-2-propanyl)oxy]-4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-5-oxopentanoic acid
(4S)-5-tert-Butoxy-4-[(tert-butoxycarbonyl)amino]-5-oxopentanoic acid (non-preferred name)
Glutamic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 1-(1,1-dimethylethyl) ester
1-tert-Butyl N-Boc-L-glutamate
L-Glutamic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 1-(1,1-dimethylethyl) ester

Biological Activity

[Description]:

Boc-Glu-OtBu is a glutamic acid derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
449.8±40.0 °C at 760 mmHg

[ Melting Point ]:
113 °C

[ Molecular Formula ]:
C₁₄H₂₅NO₆

[ Molecular Weight ]:
303.351

[ Flash Point ]:
225.8±27.3 °C

[ Exact Mass ]:
303.168182

[ PSA ]:
101.93000

[ LogP ]:
2.82

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.470

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Folding graft copolymer with pendant drug segments for co-delivery of anticancer drugs.

Biomaterials 35(25) , 7194-203, (2014)

A graft copolymer with pendant drug segments can fold into nanostructures in a protein folding-like manner. The graft copolymer is constructed by directly polymerizing γ-camptothecin-glutamate N-carbo...