Antifungal agent 53

Names

[ CAS No. ]:
2422019-76-7

[ Name ]:
Antifungal agent 53

Biological Activity

[Description]:

Antifungal agent 53 (A03) is a potent inhibitor of Candida albicans CYP51 with antifungal activity. Antifungal agent 53 prevents the formation of fungi biofilms. Antifungal agent 53 also exhibits good safety[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

[In Vitro]

Antifungal agent 53 (4 μg/mL；24 h) 对兔红细胞溶血作用[1] 。 Antifungal agent 53 (50 μg/mL，80 μg/mL；1.5-24 h) 呈剂量依赖性抑制白色念珠菌生物膜的形成[1]。

[References]

[1]. Xu H, et al. Design, synthesis, and biological evaluation of novel miconazole analogues containing selenium as potent antifungal agents. Eur J Med Chem. 2020 Jul 15;198:112360.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₁₅Cl₃N₂Se

[ Molecular Weight ]:
444.64

Related Compounds

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