2422019-76-7

2422019-76-7 structure

Name: Antifungal agent 53
Chemical Name: Antifungal agent 53
CAS Number: 2422019-76-7
Molecular Formula: C₁₈H₁₅Cl₃N₂Se
Molecular Weight: 444.64
Catalog: Signaling Pathways Anti-infection Fungal
Create Date: 2023-07-02 19:36:01
Modify Date: 2024-01-13 11:53:27
Antifungal agent 53 (A03) is a potent inhibitor of Candida albicans CYP51 with antifungal activity. Antifungal agent 53 prevents the formation of fungi biofilms. Antifungal agent 53 also exhibits good safety[1].

Name	Antifungal agent 53

Description	Antifungal agent 53 (A03) is a potent inhibitor of Candida albicans CYP51 with antifungal activity. Antifungal agent 53 prevents the formation of fungi biofilms. Antifungal agent 53 also exhibits good safety[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
In Vitro	Antifungal agent 53 (4 μg/mL；24 h) 对兔红细胞溶血作用[1] 。 Antifungal agent 53 (50 μg/mL，80 μg/mL；1.5-24 h) 呈剂量依赖性抑制白色念珠菌生物膜的形成[1]。
References	[1]. Xu H, et al. Design, synthesis, and biological evaluation of novel miconazole analogues containing selenium as potent antifungal agents. Eur J Med Chem. 2020 Jul 15;198:112360.

Molecular Formula	C₁₈H₁₅Cl₃N₂Se
Molecular Weight	444.64