PLK1/p38γ-IN-1

Names

[ CAS No. ]:
2418614-81-8

[ Name ]:
PLK1/p38γ-IN-1

Biological Activity

[Description]:

PLK1/p38γ-IN-1(compound 14) is a multitarget inhibitors ofPLK1andp38γ. PLK1/p38γ-IN-1inhibits the growth of human hepatocellular carcinoma and hepatoblastoma cells in vitro[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> MAPK/ERK Pathway >> p38 MAPK
Signaling Pathways >> Cell Cycle/DNA Damage >> Polo-like Kinase (PLK)

[References]

[1]. Cheng Z, et al. Chee Wezen X. Combination of QSAR Modeling and Hybrid-Based Consensus Scoring to Identify Dual-Targeting Inhibitors of PLK1 and p38γ. J Chem Inf Model. 2023;63(21):6912-6924.  

Chemical & Physical Properties

[ Molecular Formula ]:
C21H26ClN3O2

[ Molecular Weight ]:
387.90

Related Compounds

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