CDK7-IN-3
Names
[ CAS No. ]:
2417302-07-7
[ Name ]:
CDK7-IN-3
Biological Activity
[Description]:
CDK7-IN-3 is a selective CDK7 inhibitor with a KD of 0.059 nM. CDK7-IN-3 shows poor inhibition on CDK2 (Ki=390 nM), CDK9 (Ki=290 nM), CDK12 (Ki=78 nM). CDK7-IN-3 induce apoptosis in tumor cells and has antitumor activity.
Chemical & Physical Properties
[ Molecular Formula ]:
C23H26F3N6OP
[ Molecular Weight ]:
490.46
Related Compounds
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