YXL-13

Names

[ Name ]:
YXL-13

Biological Activity

[Description]:

YXL-13 is a potent Pseudomonas aeruginosa (PAO1) inhibitor with an IC50 value of 3.686 μM. YXL-13 can inhibit virulence factors and biofilm formation of PAO1. YXL-13 reduces the pathogenicity and drug resistance of PAO1 by inhibition of the quorum sensing (QS) system. YXL-13 can be used for researching anti-bacteria[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[Target]

IC50: 3.686 μM (Pseudomonas aeruginosa)[1]

[References]

[1]. Jiang K, Yan X, Yu J, et al. Design, synthesis, and biological evaluation of 3-amino-2-oxazolidinone derivatives as potent quorum-sensing inhibitors of Pseudomonas aeruginosa PAO1. Eur J Med Chem. 2020;194:112252.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₃H₁₅BrN₂O₄

[ Molecular Weight ]:
343.17

Related Compounds

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