cis-Khellactone

Names

[ Name ]:
cis-Khellactone

[Synonym ]:
(9R,10R)-9,10-Dihydroxy-8,8-dimethyl-9,10-dihydro-2H,8H-pyrano[2,3-f]chromen-2-one
cis-Khellactone
2H,8H-Benzo[1,2-b:3,4-b']dipyran-2-one, 9,10-dihydro-9,10-dihydroxy-8,8-dimethyl-, (9R,10R)-

Biological Activity

[Description]:

(+)-cis-Khellactone is a lactone, that can be isolated from Cordyceps. (+)-cis-Khellactone has potential medicinal properties, including anti-inflammatory, vasodilator and spasmolytic effects[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Yoshikawa M, Nishida N, Ninomiya K, Ohgushi T, Kubo M, Morikawa T, Matsuda H. Inhibitory effects of coumarin and acetylene constituents from the roots of Angelica furcijuga on D-galactosamine/lipopolysaccharide-induced liver injury in mice and on nitric oxide production in lipopolysaccharide-activated mouse peritoneal macrophages. Bioorg Med Chem. 2006 Jan 15;14(2):456-63.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
424.8±45.0 °C at 760 mmHg

[ Melting Point ]:
171.0-173.5℃

[ Molecular Formula ]:
C₁₄H₁₄O₅

[ Molecular Weight ]:
262.26

[ Flash Point ]:
162.4±22.2 °C

[ Exact Mass ]:
262.084137

[ PSA ]:
79.90000

[ LogP ]:
1.26

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.623

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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