DT-6

Names

[ CAS No. ]:
2414315-95-8

[ Name ]:
DT-6

Biological Activity

[Description]:

DT-6 is an effective TGF-β1 inhibitor. DT-6 inhibits M2 macrophage induced epithelial to mesenchymal transition and invasive migration of cancer cells. DT-6 can be used for cancer diseases research[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Stem Cell/Wnt >> TGF-beta/Smad
Signaling Pathways >> TGF-beta/Smad >> TGF-beta/Smad

[Target]

TGF-β[1]


[References]

[1]. Feng Y, et al. Degradation of intracellular TGF-β1 by PROTACs efficiently reverses M2 macrophage induced malignant pathological events. Chem Commun (Camb). 2020 Mar 5;56(19):2881-2884.  

Chemical & Physical Properties

[ Molecular Formula ]:
C89H130N20O29S2

[ Molecular Weight ]:
2008.23

Related Compounds

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