Steroid sulfatase-IN-3

Names

[ Name ]:
Steroid sulfatase-IN-3

Biological Activity

[Description]:

Steroid sulfatase-IN-3 (compound 1q) is a potent STS (Steroid sulfatase) inhibitor, with an IC50 of 25.8 nM. Steroid sulfatase-IN-3 shows antiproliferative activity against T-47D estrogen-dependent breast cancer cells, with an IC50 of 1.04 µM[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[Target]

IC50: 25.8 nM (STS, in JEG-3 cell lysate), 150.0 nM (STS, in JEG-3 cells)[1]

[References]

[1]. El-Gamal MI, et al. A new series of aryl sulfamate derivatives: Design, synthesis, and biological evaluation. Bioorg Med Chem. 2020 Apr 15;28(8):115406.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₂₁ClN₂O₄S

[ Molecular Weight ]:
384.88

Related Compounds

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