Sibiricaxanthone B

Names

[ Name ]:
Sibiricaxanthone B

[Synonym ]:
Sibiricaxanthone B
D-Glucitol, 1,5-anhydro-2-O-[(2S,3R,4R)-tetrahydro-3,4-dihydroxy-4-(hydroxymethyl)-2-furanyl]-1-C-(1,3,7-trihydroxy-9-oxo-9H-xanthen-2-yl)-, (1S)-
(1S)-1,5-Anhydro-2-O-[(2S,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)tetrahydro-2-furanyl]-1-(1,3,7-trihydroxy-9-oxo-9H-xanthen-2-yl)-D-glucitol

Biological Activity

[Description]:

Sibiricaxanthone B is a xanthone isolated from Polygala tenuifolia[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vivo]

Sibiricaxanthone B, tenuifolin, sibiricose A5, sibiricose A6, tenuifoliside A, ginsenoside Re and ginsenoside Rb1 are oral administered after Kai-Xin-San, The results indicated that Sibiricaxanthone B shows no significant differences in pharmacokinetic parameters in normal and AD rats[1].

[References]

[1]. Wang X，et al. Ultra-fast liquid chromatography with tandem mass spectrometry determination of eight bioactive components of Kai-Xin-San in rat plasma and its application to a comparative pharmacokinetic study in normal and Alzheimer's disease rats.J Sep Sci. 2017 May;40(10):2131-2140

Chemical & Physical Properties

[ Density]:
1.9±0.1 g/cm3

[ Boiling Point ]:
964.4±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₄H₂₆O₁₄

[ Molecular Weight ]:
538.455

[ Flash Point ]:
328.7±27.8 °C

[ Exact Mass ]:
538.132263

[ LogP ]:
0.14

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.787

[ Storage condition ]:
2-8℃

Related Compounds

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