Anticancer agent 127
Names
[ CAS No. ]:
2410953-19-2
[ Name ]:
Anticancer agent 127
Biological Activity
[Description]:
Anticancer agent 127 (142D6) is an IAP inhibitor that covalently targets the BIR3 domains of XIAP, cIAP1, and cIAP2. Anticancer agent 127 targets the BIR3 domains of XIAP, cIAP1, and cIAP2 with IC50s of 12 nM, 14 nM, and 9 nM, respectively. Anticancer agent 127 has anticancer effects[1].
[Related Catalog]:
[Target]
IC50: 12 nM (XIAP-BIR3), 14 nM (cIAP1-BIR3), and 9 nM (cIAP2-BIR3)[1]
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C26H37FN4O6S
[ Molecular Weight ]:
552.66