HDAC-IN-26

Names

[ CAS No. ]:
2410542-97-9

[ Name ]:
HDAC-IN-26

Biological Activity

[Description]:

HDAC-IN-26 is a highly selective class I HDAC inhibitor with an EC50 value of 4.7 nM.

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Cell Cycle/DNA Damage >> HDAC

Signaling Pathways >> Epigenetics >> HDAC

[References]

[1]. Liu J, Kelly J, Yu W, Clausen D, Yu Y, Kim H, Duffy JL, Chung CC, Myers RW, Carroll S, Klein DJ, Fells J, Holloway MK, Wu J, Wu G, Howell BJ, Barnard RJO, Kozlowski JA. Selective Class I HDAC Inhibitors Based on Aryl Ketone Zinc Binding Induce HIV-1 Protein for Clearance. ACS Med Chem Lett. 2020 Jun 22;11(7):1476-1483.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₂₈FN₅O₃

[ Molecular Weight ]:
453.51

Related Compounds

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