Topoisomerase I inhibitor 6

Names

[ CAS No. ]:
2393082-56-7

[ Name ]:
Topoisomerase I inhibitor 6

Biological Activity

[Description]:

Topoisomerase I inhibitor 6 (Compound 3) is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 6 is able to trap DNA-Top1 cleavage complex and found to be less cytotoxic in non-cancerous cell line. Topoisomerase I inhibitor 6 has the potential for the research of cancer diseases[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase

[References]

[1]. Kundu B, et al. Development of a metabolically stable topoisomerase I poison as anticancer agent. Eur J Med Chem. 2020 Sep 15;202:112551. doi: 10.1016/j.ejmech.2020.112551.

Chemical & Physical Properties

[ Molecular Formula ]:
C23H21N7O

[ Molecular Weight ]:
411.46

Related Compounds

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