Antibacterial agent 12

Names

[ Name ]:
Antibacterial agent 12

Biological Activity

[Description]:

Antibacterial agent 12, a biaryloxazolidinone analogue, is an antibacterial agent against antibiotic-susceptible and antibiotic-resistant Gram-positive bacteria[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Antibacterial agent 12 (compound 14a-7) exhibits a MIC value of 0.125 μg/mL against S.aureus[1]. Antibacterial agent 12 (compound 14a-7) is stable in human liver microsome. Antibacterial agent 12 exhibits lower inhibitory activity against human MAO-A compared to Linezolid[1].

[References]

[1]. Yachuang Wu, et al. Optimization of biaryloxazolidinone as promising antibacterial agents against antibiotic-susceptible and antibiotic-resistant gram-positive bacteria. Eur J Med Chem. 2020 Jan 1;185:111781.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₄FN₅O₅S

[ Molecular Weight ]:
489.52

Related Compounds

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