Homovanillyl alcohol

Names

[ Name ]:
Homovanillyl alcohol

[Synonym ]:
MFCD00002903
EINECS 219-175-1
3-METHOXY-4-HYDROXYPHENYLETHANOL
2-(4-hydroxy-3-methoxyphenyl)ethanol
3-methoxy-4-hydroxyphenethyl alcohol
4-Hydroxy-3-methoxyphenylethyl alcohol
4-Hydroxy-3-methoxyphenethyl alcohol
4-(2-Hydroxyethyl)-2-methoxyphenol
4-Hydroxy-3-methoxyphenethanol
Homovanillyl alcohol
Homovanillic alcohol
Benzeneethanol, 4-hydroxy-3-methoxy-
MOPET
Benzeneethanol,4-hydroxy-3-methoxy-

Biological Activity

[Description]:

Homovanillyl alcohol is a biological metabolite of Hydroxytyrosol. Hydroxytyrosol is a phenolic compound that is present in virgin olive oil (VOO) and wine. Homovanillyl alcohol protects red blood cells (RBCs) from oxidative injury and has protective effect on cardiovascular disease[1][2].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

[References]

[1]. Fátima Paiva-Martins, et al. Protective Activity of Hydroxytyrosol Metabolites on Erythrocyte Oxidative-Induced Hemolysis. J Agric Food Chem. 2013 Jul 10;61(27):6636-42.

[2]. Rafael De la Torre, et al. Protective Effect of Homovanillyl Alcohol on Cardiovascular Disease and Total Mortality: Virgin Olive Oil, Wine, and Catechol-Methylation. Am J Clin Nutr. 2017 Jun;105(6):1297-1304.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
316.8±27.0 °C at 760 mmHg

[ Melting Point ]:
40-42 °C(lit.)

[ Molecular Formula ]:
C₉H₁₂O₃

[ Molecular Weight ]:
168.190

[ Flash Point ]:
145.4±23.7 °C

[ Exact Mass ]:
168.078644

[ PSA ]:
49.69000

[ LogP ]:
0.33

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.559

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2909499000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2909499000

[ Summary ]:
2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

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Related Compounds

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