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CCT373567

Names

[ CAS No. ]:
2378853-67-7

[ Name ]:
CCT373567

Biological Activity

[Description]:

CCT373567 is a potent degrader of transcriptional repressor BCL6, with an IC50 of 2.9 nM. CCT373567 exhibits antiproliferative activity[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Bcl-2 Family
Research Areas >> Cancer

[References]

[1]. Huckvale R, et, al. Improved Binding Affinity and Pharmacokinetics Enable Sustained Degradation of BCL6 In Vivo. J Med Chem. 2022 Jun 23;65(12):8191-8207.

Chemical & Physical Properties

[ Molecular Formula ]:
C26H29ClF2N6O3

[ Molecular Weight ]:
547.00


Related Compounds

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