2378853-67-7

2378853-67-7 structure

2378853-67-7 structure

Name: CCT373567
Chemical Name: CCT373567
CAS Number: 2378853-67-7
Molecular Formula: C₂₆H₂₉ClF₂N₆O₃
Molecular Weight: 547.00
Catalog: Signaling Pathways Apoptosis Bcl-2 Family
Create Date: 2022-08-16 08:18:03
Modify Date: 2023-02-13 09:46:44
CCT373567 is a potent degrader of transcriptional repressor BCL6, with an IC50 of 2.9 nM. CCT373567 exhibits antiproliferative activity[1].

Name	CCT373567

Description	CCT373567 is a potent degrader of transcriptional repressor BCL6, with an IC50 of 2.9 nM. CCT373567 exhibits antiproliferative activity[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Bcl-2 Family Research Areas >> Cancer
References	[1]. Huckvale R, et, al. Improved Binding Affinity and Pharmacokinetics Enable Sustained Degradation of BCL6 In Vivo. J Med Chem. 2022 Jun 23;65(12):8191-8207.

Molecular Formula	C₂₆H₂₉ClF₂N₆O₃
Molecular Weight	547.00