MS21

Names

[ Name ]:
MS21

Biological Activity

[Description]:

MS21, a novel degrader of AKT, selectively inhibits the growth of PI3K/PTEN pathway-mutant cancers with wild-type KRAS and BRAF.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC

[References]

[1]. Xu J, et al. AKT Degradation Selectively Inhibits the Growth of PI3K/PTEN Pathway-Mutant Cancers with Wild-Type KRAS and BRAF by Destabilizing Aurora Kinase B. Cancer Discov. 2021 Jul 23.

Chemical & Physical Properties

[ Molecular Formula ]:
C₅₈H₇₉ClN₁₂O₆S

[ Molecular Weight ]:
1107.84

Related Compounds

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