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2376137-05-0

2376137-05-0 structure
2376137-05-0 structure
  • Name: MS21
  • Chemical Name: MS21
  • CAS Number: 2376137-05-0
  • Molecular Formula: C58H79ClN12O6S
  • Molecular Weight: 1107.84
  • Catalog: Signaling Pathways PROTAC PROTAC
  • Create Date: 2022-01-29 16:37:01
  • Modify Date: 2025-08-25 19:41:14
  • MS21, a novel degrader of AKT, selectively inhibits the growth of PI3K/PTEN pathway-mutant cancers with wild-type KRAS and BRAF.

Name MS21
Description MS21, a novel degrader of AKT, selectively inhibits the growth of PI3K/PTEN pathway-mutant cancers with wild-type KRAS and BRAF.
Related Catalog
References

[1]. Xu J, et al. AKT Degradation Selectively Inhibits the Growth of PI3K/PTEN Pathway-Mutant Cancers with Wild-Type KRAS and BRAF by Destabilizing Aurora Kinase B. Cancer Discov. 2021 Jul 23.

Molecular Formula C58H79ClN12O6S
Molecular Weight 1107.84
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