TNIK-IN-6

Names

[ CAS No. ]:
2375196-40-8

[ Name ]:
TNIK-IN-6

Biological Activity

[Description]:

TNIK-IN-6 (Compound 9) is an inhibitor of Traf2 and Nck-interacting kinase (TNIK) and , with IC50 of 0.93 μM, that plays important roles in neurological and psychiatric disorders[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[References]

[1]. Koc-Kan Ho, et al. Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors. Bioorg Med Chem Lett. 2013 Jan 15;23(2):569-73.  

[2]. Jon Read, et al. Tool inhibitors and assays to interrogate the biology of the TRAF2 and NCK interacting kinase. Bioorg Med Chem Lett. 2019 Aug 1;29(15):1962-1967.  

Chemical & Physical Properties

[ Molecular Formula ]:
C13H8BrFN4

[ Molecular Weight ]:
319.13

Related Compounds

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