(2H3)Acetamide

Names

[ Name ]:
(2H3)Acetamide

[Synonym ]:
Acetamidoxim,Hydrochlorid
2-Trideutero-acetamid
2,2,2-trideuterio-acetamide
N'-hydroxyethanimidamide hydrochloride
trideuteroacetamide
2.2.2-Trideuterio-acetamid
N-hydroxyacetamidine monohydrochloride
acetamide oxime hydrochloride
N-hydroxy-acetamidine,hydrochloride
Acetamidoxime monohydrochloride
<2,2,2-2H3>-Acetamid
Acetamide-d
(H)Acetamide
acetamidoxime hydrochloride
acetamide-d3
N'-hydroxyacetimidamide hydrochloride
C,C,C-Trideuterio-acetamid

Biological Activity

[Description]:

Acetamide-2,2,2-d3 is the deuterium labeled Acetamide-2,2,2-d3[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
221.1±0.0 °C at 760 mmHg

[ Melting Point ]:
78-80ºC(lit.)

[ Molecular Formula ]:
C₂H₂D₃NO

[ Molecular Weight ]:
62.086

[ Flash Point ]:
90.1±18.4 °C

[ Exact Mass ]:
62.055943

[ PSA ]:
43.09000

[ LogP ]:
-1.23

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.393

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H351

[ Precautionary Statements ]:
P281

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
40

[ Safety Phrases ]:
36/37

[ RIDADR ]:
UN 3077 9/PG 3