DL-O-Tyrosine

Names

[ Name ]:
DL-O-Tyrosine

[Synonym ]:
2,5-Diaminopentanoic acid
EINECS 219-134-8
2-Amino-3-(2-hydroxyphenyl)propionic Acid
L-2,5-Diaminopentanoic acid
MFCD00021725
D,L-o-tyrosine
DL-o-Tyrosine

Biological Activity

[Description]:

DL-O-Tyrosine is a tyrosine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[Target]

Human Endogenous Metabolite

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.333g/cm3

[ Boiling Point ]:
369ºC at 760mmHg

[ Melting Point ]:
260ºC

[ Molecular Formula ]:
C₉H₁₁NO₃

[ Molecular Weight ]:
181.18900

[ Flash Point ]:
177ºC

[ Exact Mass ]:
181.07400

[ PSA ]:
83.55000

[ LogP ]:
1.04690

[ Vapour Pressure ]:
5.14E-18mmHg at 25°C

[ Storage condition ]:
-20°C Freezer

[ Water Solubility ]:
Soluble in water, and DMSO (Heated).

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YP2285000

CHEMICAL NAME :: o-Tyrosine, DL-

CAS REGISTRY NUMBER :: 2370-61-8

LAST UPDATED :: 197901

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C9-H11-N-O3

MOLECULAR WEIGHT :: 181.21

WISWESSER LINE NOTATION :: QVYZ1R BQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 320 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#02426

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
YP2285000

[ HS Code ]:
2922509090

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

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J. Chromatogr. A. 1218(23) , 3689-94, (2011)

We report a novel two-dimensional (2D) separation strategy aimed at improving the detectability of liquid chromatography mass spectrometry (LC–MS) for metabolome analysis. It is based on the use of io...

Concomitant tumor resistance: the role of tyrosine isomers in the mechanisms of metastases control.

Cancer Res. 72(5) , 1043-50, (2012)

Concomitant tumor resistance (CR) is a phenomenon in which a tumor-bearing host is resistant to the growth of secondary tumor implants and metastasis. Although previous studies indicated that T-cell-d...

Mass spectrometric quantification of 3-nitrotyrosine, ortho-tyrosine, and o,o'-dityrosine in brain tissue of 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-treated mice, a model of oxidative stress in Parkinson's disease.

J. Biol. Chem. 274(49) , 34621-8, (1999)

Oxidative stress is implicated in the death of dopaminergic neurons in Parkinson's disease and in the 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine (MPTP) model of Parkinson's disease. Oxidative speci...