VPC-70619

Names

[ Name ]:
VPC-70619

Biological Activity

[Description]:

VPC-70619 is a potent, orally active N-Myc inhibitor. VPC-70619 blocks the N-Myc-Max heterocomplex from binding to DNA E-boxes and demonstrated strong inhibition activity against N-Myc-dependent cell lines as well as high bioavailability in both oral and intraperitoneal administration[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Apoptosis >> c-Myc

[References]

[1]. Ton AT, et al. Development of VPC-70619, a Small-Molecule N-Myc Inhibitor as a Potential Therapy for Neuroendocrine Prostate Cancer. Int J Mol Sci. 2022;23(5):2588. Published 2022 Feb 26.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₈ClF₃N₄O

[ Molecular Weight ]:
364.71

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.