Biotin-PEG4-Dde-TAMRA-PEG3-Azide

Names

[ CAS No. ]:
2353409-56-8

[ Name ]:
Biotin-PEG4-Dde-TAMRA-PEG3-Azide

Biological Activity

[Description]:

Biotin-PEG4-Dde-TAMRA-PEG3-Azide is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[References]

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Chemical & Physical Properties

[ Molecular Formula ]:
C69H96N12O17S

[ Molecular Weight ]:
1397.64

Related Compounds