U-99194 maleate

Names

[ CAS No. ]:
234757-41-6

[ Name ]:
U-99194 maleate

[Synonym ]:
CRF (human,rat)
5,6-Dimethoxy-2-(di-n-propylamino)indan maleate salt

Chemical & Physical Properties

[ Melting Point ]:
146 - 147 °C

[ Molecular Formula ]:
C₂₁H₃₁NO₆

[ Molecular Weight ]:
393.47400

[ Exact Mass ]:
393.21500

[ PSA ]:
96.30000

[ LogP ]:
3.00480

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Dopaminergic D2-like agonists produce yawning in the myelin mutant taiep and Sprague–Dawley rats

Pharmacol. Biochem. Behav. 102(1) , 118-23, (2012)

Systemic administration of D2-like dopaminergic-receptor agonists increases yawning behavior. However, only a few studies have been done in animals with pathological conditions. The taiep rat is a mye...

Presynaptic dopaminergic agonists increased gripping-generated immobility episodes in the myelin-mutant taiep rat.

Neurosci. Lett. 483(3) , 189-92, (2010)

The taiep rat is a myelin mutant whose immobility episodes (IEs) can be caused by gripping them by the tail. Electroencephalographic recordings during IEs show a rapid-eye movement sleep-like pattern,...

The dopamine D3-receptor: a postsynaptic receptor inhibitory on rat locomotor activity.

J. Neural Transm. Gen. Sect. 94 , 11-19, (1993)

We report on the pharmacological effects of the 20 fold D3 vs. D2 dopamine receptor preferring compound U99194A. It is shown that U99194A increases rat locomotor activity at doses that do not increase...